A growing number of studies have found elevated risks of central nervous system (CNS) diseases such as Parkinson's disease and Alzheimer's disease linked to air pollution, which is traditionally known for its adverse effects mainly on the cardiopulmonary systems. Neuropulmonology refers to the complex interconnection between the CNS and the respiratory system. Currently, there are three hypothesized pathways of particulate matter (PM)'s effects on the brain. First, the olfactory bulb is considered to be one route by which inhaled PM can be directly translocated into the brain. Second, smaller PM can directly cross the blood-brain barrier (BBB), which is responsible for keeping harmful particles and chemicals out of the brain. Third, PM directly/indirectly damages barriers, such as the BBB and nasal epithelium. However, the underlying mechanism of CNS toxicity caused by PM remains unclear. Importantly, physicochemical characteristics of PM may play an essential role in regulation of neuropulmonary toxicity. The prime aim of this special issue is a timely collection of research studies on PM-related pulmonary, CNS and neuropulmonary health. The topics include but are not limited to:
AAQR focuses on aerosol and air quality and is indexed in SCI with the impact factor of 2.589 in 2017 JCR. AAQR is an open access journal supported by the publication fee charged to the corresponding author of the accepted papers. The Guidelines for Authors for submitting a manuscript can be found on the website of AAQR (http://aaqr.org). The deadline for manuscript submission is Oct. 31, 2019. Manuscripts submitted after the deadline are considered only when the space is available. The targeted publication date is May 2020.
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