Articles online

PAHs in Size Fractionate Mainstream Cigarette Smoke, Predictive Deposition and Associated Inhalation Risk

Category: Air Toxics

Volume: 17 | Issue: 1 | Pages: 176-186
DOI: 10.4209/aaqr.2015.03.0156
PDF | RIS | BibTeX

Mahesh Tiwari, Sanjay Kumar Sahu, Gauri Girish Pandit

  • Environmental Monitoring and Assessment Section, Health Safety and Environment Group, Bhabha Atomic Research Centre Mumbai, 400085, India


Mass and PAHs size distributions of mainstream cigarette smoke (MCS) were evaluated.
Distributions peaked at two sizes bin 0.3–0.1 µm and 0.75–1.13 µm aerodynamic diameters.
B[a]Peq PAHs emission in MCS was found to be 110 ± 12 ng cigarette–1 for tested brands.
Size dependent deposition fractions in respiratory tract were calculated using MPPD model.
ILCR for PAHs exposure of smoking cigarette were ranged from 1.3 × 10–5 to 3.9 × 10–5.


Size fractionated mainstream cigarette smoke (MCS) samples were collected with variable configuration cascade impactor (VCCI). Samples were extracted ultrasonically and analysis of sixteen priority polycyclic aromatic hydrocarbons (PAHs) was performed using high performance liquid chromatography (HPLC) coupled with UV-visible detector. Identification of PAHs were also carried out using gas chromatography coupled with mass spectrometry (GC-MS) technique. Data of size fractionate PAHs in MCS were used to calculate size dependent deposition in different compartment of human respiratory tract using multiple path particle dosimetry (MPPD) model. All brand cigarette smoke showed similar trends of particle mass and PAHs size distribution peaked at two sizes 0.3–0.1 µm and 0.75–1.13 µm aerodynamic diameter. All tested brands of MCS recorded around 48.75% of two and three-ring PAHs, 23 to 25% four-ring PAHs and 26–27% five and higher rings PAHs of total analyzed PAHs. Benzo[a]pyrene equivalent (B[a]Peq) PAHs emission in MCS was found to be 110 ± 12 (µ ± 1σ) ng per cigarette for tested brands. Total deposition fraction in respiratory tract was found to be 0.69 ± 0.26 for tested size ranges. Average 5th and 95th percentile values of incremental lifetime cancer risk (ILCR) for smoker due to PAHs exposure were found to be 1.3 × 10–5 to 3.9 × 10–5 respectively for tested cigarette brands.


Carcinogens Liquid chromatography/Mass spectrometry Respiratory health ILCR MPPD

Related Article

Size Distribution of Inorganic Elements in Bottom Ashes from Seven Types of Bio-Fuels across Beijing-Tianjin-Hebei Region, China

Zhiyong Li , Huiqiao Ma, Lin Fan, Peng Zhao, Lei Wang, Yunjun Jiang, Caixiu An, Aiqin Liu, Zishu Hu, Hui Jin
Volume: 17 | Issue: 10 | Pages: 2450-2462
DOI: 10.4209/aaqr.2017.08.0296

Seasonal Trends of Atmospheric PAHs in Five Asian Megacities and Source Detection Using Suitable Biomarkers

Mahua Saha, Dusmant Maharana, Rina Kurumisawa, Hideshige Takada , Bee Geok Yeo, Andrea C. Rodrigues, Badal Bhattacharya, Hidetoshi Kumata, Tomoaki Okuda, Kebin He, Yongliang Ma, Fumiyuki Nakajima, Mohamad Pauzi Zakaria, Duong Hoang Giang, Pham Hung Viet
Volume: 17 | Issue: 9 | Pages: 2247-2262
DOI: 10.4209/aaqr.2017.05.0163
PDF | Supplemental material