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Short-Term Effects of Fine Particulate Air Pollution on Ischemic Heart Disease Hospitalizations in Taipei: A Case-Crossover Study

Category: Articles

Volume: 13 | Issue: 5 | Pages: 1563-1569
DOI: 10.4209/aaqr.2013.01.0013

Export Citation:  RIS | BibTeX

Hui-Fen Chiu1, Chiung-Yu Peng2, Trong-Neng Wu3,4, Chun-Yuh Yang 2,4

  • 1 Department of Pharmacology, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
  • 2 Department of Public Health, College of Health Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan
  • 3 Department of Public Health, China Medical University, Taichung, Taiwan
  • 4 Division of Environmental Health and Occupational Medicine, National Health Research Institute, Miaoli, Taiwan


This study was undertaken to determine whether there was a correlation between fine particles (PM2.5) levels and hospital admissions for ischemic heart disease (IHD) in Taipei, Taiwan. Hospital admissions for IHD and ambient air pollution data for Taipei were obtained for the period from 2006–2010. The relative risk of hospital admissions was estimated using a case-crossover approach, controlling for weather variables, day of the week, seasonality, and long-term time trends. For the single pollutant model (without adjustment for other pollutants), increased IHD admissions were significantly associated with PM2.5 on both warm (> 23°C) and cool days (< 23°C), with an interquartile range increase associated with a 12% (95% CI = 10%–14%) and 4% (95% CI = 2%–6%) increase in IHD admissions, respectively. In the two-pollutant models, PM2.5 remained significant after the inclusion of SO2 or O3 both on warm and cool days. This study provides evidence that higher levels of PM2.5 increase the risk of hospital admissions for IHD.


Fine particulate Air pollution Ischemic heart disease Case-crossover Hospital admissions

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